10.1371/journal.pone.0018017.g005
Kiran Kumar Velpula
Kiran
Kumar Velpula
Venkata Ramesh Dasari
Venkata
Ramesh Dasari
Andrew J. Tsung
Andrew
J. Tsung
Christopher S. Gondi
Christopher
S. Gondi
Jeffrey D. Klopfenstein
Jeffrey
D. Klopfenstein
Sanjeeva Mohanam
Sanjeeva
Mohanam
Jasti S. Rao
Jasti
S. Rao
hUCBSC treatment downregulates cyclin D1 <i>in vitro</i>
and <i>in vivo</i>.
Public Library of Science
2011
downregulates
cyclin
d1
2011-03-24 00:15:48
Figure
https://plos.figshare.com/articles/figure/_hUCBSC_treatment_downregulates_cyclin_D1_in_vitro____and_in_vivo_/460948
<p>(<b>A</b>) Immunocytochemistry of single and co-cultures of U251
and 5310 cells for the expression of cyclin D1 and CD81. Cyclin D1 is
conjugated with Alexa Fluor-594 (red), and CD81 is conjugated with Alexa
Flour-488 (green). Inset pictures show magnified images.
Bar = 200 µm (<b>B</b>) Nude mice with
pre-established intracranial human glioma tumors (U251 or 5310) were
treated with hUCBSC by intracranial injection (2×10<sup>5</sup>).
Fourteen days after hUCBSC administration, the brains were harvested and
sectioned and immunoprobed for cyclin D1 and appropriate secondary
antibodies. Inset pictures show magnified images. Bar
= 200 µm. Each experiment was performed in
triplicates with each sample (n = 3).</p>