10.6084/m9.figshare.4602232.v1
Kirstie Whitaker
Kirstie
Whitaker
Checking your working: a reproducible and replicable neuroimaging study of adolescent brain development.
figshare
2017
adolescence
brain development
cortical thickness
gene expression
reproducible
replication
Neuroscience
Psychiatry (incl. Psychotherapy)
2017-02-01 14:21:59
Presentation
https://figshare.com/articles/presentation/Checking_your_working_a_reproducible_and_replicable_neuroimaging_study_of_adolescent_brain_development_/4602232
Adolescence is a period of human brain growth and high incidence of mental health disorders. In 2016 the <a href="http://www.nspn.org.uk/" target="_blank">Neuroscience in Psychiatry Network</a>
published a study of adolescent brain development which showed that the
hubs of the structural connectome are late developing and are found in
association cortex (<a href="http://dx.doi.org/10.1073/pnas.1601745113" target="_blank">http://dx.doi.org/10.1073/pnas.1601745113</a>).
Furthermore these regions are enriched for genes related to
schizophrenia. In this presentation Dr Kirstie Whitaker will demonstrate
how this work is supported by open data and analysis code, and that the
results replicate in two independent cohorts of teenagers. She will
encourage CamBRAIN members to take steps towards ensuring that their
work meets these standards for open and reproducible science in 2017 and
beyond.