10.6084/m9.figshare.4591843.v3 P. Sambasiva Rao P. Sambasiva Rao K. Chinna Ashalu K. Chinna Ashalu G. Jitender Dev G. Jitender Dev N. Ravi Kumar N. Ravi Kumar P. V. S. S. Srinivas P. V. S. S. Srinivas B. V. Thomas B. V. Thomas B. Narsaiah B. Narsaiah Efficient method for the synthesis of 1,2,3-triazole functionalized isoxazolidine derivatives by 1,3-dipolar cycloaddition of nitrones with terminal olefins Taylor & Francis Group 2017 1,3-Dipolar cycloaddition isoxazolidine nitrones olefins 1,2,3-triazole 2017-02-15 19:37:42 Journal contribution https://tandf.figshare.com/articles/journal_contribution/Efficient_method_for_the_synthesis_of_1_2_3-triazole_functionalized_isoxazolidine_derivatives_by_1_3-dipolar_cycloaddition_of_nitrones_with_terminal_olefins/4591843 <p>1-Phenyl-1,2,3-triazole-4-carbaldehyde <b>1</b> was treated with different <i>N</i>-alkyl hydroxylamine hydrochlorides <b>2</b> using NaHCO<sub>3</sub> to obtain 1,2,3-triazole substituted <i>N</i>-alkyl nitrones <b>3a–c</b>. The nitrones <b>3a–c</b> were further reacted with different substituted olefins and furnished 2-alkyl-3-(1-phenyl-1<i>H</i>-1,2,3-triazol-4-yl)-5-(substituted)isoxazolidine derivatives <b>4a–p</b> in high yields via 1,3-dipolar cycloaddition reaction.</p>