TY - DATA T1 - Proteomic Analysis of Kveim Reagent Identifies Targets of Cellular Immunity in Sarcoidosis - Fig 4 PY - 2017/01/23 AU - Christian Eberhardt AU - Muhunthan Thillai AU - Robert Parker AU - Nazneen Siddiqui AU - Lee Potiphar AU - Rob Goldin AU - John F. Timms AU - Athol U. Wells AU - Onn M. Kon AU - Melissa Wickremasinghe AU - Donald Mitchell AU - Mark E. Weeks AU - Ajit Lalvani UR - https://plos.figshare.com/articles/figure/Proteomic_Analysis_of_Kveim_Reagent_Identifies_Targets_of_Cellular_Immunity_in_Sarcoidosis_-_Fig_4/4583389 DO - 10.1371/journal.pone.0170285.g004 L4 - https://ndownloader.figshare.com/files/7477738 KW - identifier PXD 005150. KW - sarcoidosis spleen tissue KW - alpha-actinin -4. Conclusions Stimulation KW - vimentin stimulation KW - 2 D-DIGE KW - sarcoidosis PBMCs KW - Multiplex Cytokine Assay KW - cytokine secretion KW - IFN KW - Kv-specific proteins KW - Kveim Reagent Identifies KW - sarcoidosis PBMCs vs KW - 1 D-SDS-PAGE KW - pg KW - control PBMCs KW - TNF -α secretion KW - Methods Kv extracts KW - Sarcoidosis Background Kveim-reagent KW - 74 sarcoidosis tissue-specific proteins KW - pro-inflammatory cytokine secretion KW - sarcoidosis patients vs KW - Peripheral Blood Mononuclear Cells N2 - Immunohistochemical staining of spleen tissue shows increased abundance of vimentin in sarcoidosis spleens at 200 x (Fig 4a) and 400 x magnification (Fig 4b) compared to healthy spleen tissue at the same magnifications (Fig 4c and 4d). ER -