Additional file 2: of iRegNet3D: three-dimensional integrated regulatory network for the genomic analysis of coding and non-coding disease mutations LiangSiqi TippensNathaniel ZhouYaoda MortMatthew StensonPeter CooperDavid YuHaiyuan 2017 Supplementary figure: a. Odds ratio for the distribution of transcription factor HGMD missense mutations in different interaction interfaces using only interfaces with co-crystal structures. ***P < 10–3. P values calculated using the Z-test on log odds ratio. Error bars indicate ± standard error (SE). b. Odds ratio for the distribution of transcription factor ESP missense SNPs in different interaction interfaces using only interfaces with co-crystal structures. Error bars indicate ± SE. (PDF 301 kb)