10.6084/m9.figshare.c.3667540_D4.v1 Nora Huang Nora Huang Melanie Kny Melanie Kny Fabian Riediger Fabian Riediger Katharina Busch Katharina Busch Sibylle Schmidt Sibylle Schmidt Friedrich Luft Friedrich Luft Hortense Slevogt Hortense Slevogt Jens Fielitz Jens Fielitz Additional file 2: of Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy Springer Nature 2017 Sepsis IL-1β Muscle weakness ICUAW 2017-01-17 05:00:00 Figure https://springernature.figshare.com/articles/figure/Additional_file_2_of_Deletion_of_Nlrp3_protects_from_inflammation-induced_skeletal_muscle_atrophy/4560154 Polymicrobial sepsis increases Nlrp3, Il1b, and Il6 expression in the muscle. Twelve-week-old male C57B16/J mice were subjected to cecal ligation and puncture (CLP) or sham surgery (sham), as indicated. (A) qRT-PCR analysis of Nlrp3, IL-1β, and Il6 expression in gastrocnemius/plantaris (GP) and (B) tibialis anterior (TA) muscles of sham (n = 5) and CLP (n = 5) mice 4 days after surgery. mRNA expression was normalized to Gapdh. Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001. (EPS 1161 kb)