10.6084/m9.figshare.c.3667540_D4.v1
Nora Huang
Nora
Huang
Melanie Kny
Melanie
Kny
Fabian Riediger
Fabian
Riediger
Katharina Busch
Katharina
Busch
Sibylle Schmidt
Sibylle
Schmidt
Friedrich Luft
Friedrich
Luft
Hortense Slevogt
Hortense
Slevogt
Jens Fielitz
Jens
Fielitz
Additional file 2: of Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy
Springer Nature
2017
Sepsis
IL-1β
Muscle weakness
ICUAW
2017-01-17 05:00:00
Figure
https://springernature.figshare.com/articles/figure/Additional_file_2_of_Deletion_of_Nlrp3_protects_from_inflammation-induced_skeletal_muscle_atrophy/4560154
Polymicrobial sepsis increases Nlrp3, Il1b, and Il6 expression in the muscle. Twelve-week-old male C57B16/J mice were subjected to cecal ligation and puncture (CLP) or sham surgery (sham), as indicated. (A) qRT-PCR analysis of Nlrp3, IL-1β, and Il6 expression in gastrocnemius/plantaris (GP) and (B) tibialis anterior (TA) muscles of sham (n = 5) and CLP (n = 5) mice 4 days after surgery. mRNA expression was normalized to Gapdh. Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001. (EPS 1161 kb)