%0 Figure %A Huber, Bettina %A Schellenbacher, Christina %A Shafti-Keramat, Saeed %A Jindra, Christoph %A Christensen, Neil %A Kirnbauer, Reinhard %D 2017 %T Transmission electron microscopy images of chimeric VLP. %U https://plos.figshare.com/articles/figure/Transmission_electron_microscopy_images_of_chimeric_VLP_/4521965 %R 10.1371/journal.pone.0169533.g002 %2 https://ndownloader.figshare.com/files/7322681 %K HPV 4 challenge %K chimeric proteins self-assembled %K capsid proteins %K non-melanoma skin cancer %K HPV 16 L 1 VLP %K murine PsV challenge model %K VLP-raised NZW rabbit %K 12 novel beta PsV types %K mucosal HPV infections %K HPV 16L VLP %K RG 1 homolog %K RG 1-based VLP %K Chimeric L 2-Based Virus-Like Particle %K HPV 5L VLP cross-protected %K HPV 5L aa 53-72 epitope %K cutaneous HPV types %K HPV 16 L 2 cross-neutralization epitope RG 1 %K L 2 peptide %K HPV 1L VLP cross-protected %K species beta HPV %K 18 L 1 VLP scaffolds %K ELISA %K HPV 17 RG 1 epitope %K cutaneous HPV 4 RG 1 homolog %K DE surface loops %K Experimental papillomavirus vaccines %K generation vaccine candidates %K target cutaneous HPV infections %K target cutaneous HPV %K Licensed HPV vaccines %K type-common neutralization epitopes %K Vaccines Targeting Cutaneous Human Papillomaviruses %K L 1 fusion proteins %K target heterologous HPV %K NMSC %K L 2-based pseudovirion %X

Purified preparations of HPV5L1-17RG1 (A), HPV16L1-17RG1 (B), HPV1L1-4RG1 (C), HPV16L1-5L2(aa53-72) (D) and HPV18L1-5L2(aa53-72) (E) were negatively stained and visualized at 30,000-fold magnification. The size bars represent 200nm. +, tubular structures composed of pentamers; *, co-purified baculovirus contaminant.

%I PLOS ONE