TY - DATA T1 - IC50s of human DIPG cell models with Panobinostat treatment. PY - 2017/01/04 AU - Tammy Hennika AU - Guo Hu AU - Nagore G. Olaciregui AU - Kelly L. Barton AU - Anahid Ehteda AU - Arjanna Chitranjan AU - Cecilia Chang AU - Andrew J. Gifford AU - Maria Tsoli AU - David S. Ziegler AU - Angel M. Carcaboso AU - Oren J. Becher UR - https://plos.figshare.com/articles/dataset/IC50s_of_human_DIPG_cell_models_with_Panobinostat_treatment_/4517735 DO - 10.1371/journal.pone.0169485.t001 L4 - https://ndownloader.figshare.com/files/7309883 KW - Pre-Clinical Study KW - vivo analyses KW - H 3.3-K tumors KW - H 3.3-WT expression KW - panobinostat potently KW - brainstem glioma KW - PDGF-B KW - target inhibition KW - BSG mouse model KW - histone deacetylase inhibitor KW - brain tumor-related deaths KW - pontine glioma KW - brain tissue KW - murine DIPG cells KW - tumor cells KW - impact survival KW - vivo efficacy studies KW - H 3.3-K orthotopic DIPG xenograft model KW - well-tolerated doses KW - cell proliferation KW - p 53 loss KW - vehicle-treated mice KW - tumor-bearing mice KW - orthotopic xenograft models KW - dose de-escalation KW - Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models Background Diffuse KW - murine tumor cells KW - H 3 acetylation KW - ectopic H 3.3-K KW - brainstem tumor tissue N2 - IC50s of human DIPG cell models with Panobinostat treatment. ER -