10.6084/m9.figshare.4503029.v1
Bo Chen
Bo
Chen
Mengping Guo
Mengping
Guo
Yongju Wen
Yongju
Wen
Xiuli Shen
Xiuli
Shen
Xiuling Zhou
Xiuling
Zhou
Meiyun Lv
Meiyun
Lv
Efficient P, O chelate palladium(II)/AgNO<sub>3</sub> cocatalyzed homocoupling of aromatic terminal alkynes in aqueous media under ambient atmosphere
Taylor & Francis Group
2016
Aromatic terminal alkynes
P,O chelate Pd(II) complex/AgNO3 cocatalyst
homocoupling reaction
1,4-disubstituted-1,3-diynes
2016-12-29 16:12:04
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Efficient_P_O_chelate_palladium_II_AgNO_sub_3_sub_cocatalyzed_homocoupling_of_aromatic_terminal_alkynes_in_aqueous_media_under_ambient_atmosphere/4503029
<p>A new and efficient protocol for the P, O chelate Pd(II)/AgNO<sub>3</sub> cocatalyzed oxidative homocoupling reaction of aromatic terminal alkynes in the synthesis of symmetrical 1,4-disubstituted-1,3-diynes was described in aqueous media under ambient atmosphere. The results showed that both NEt<sub>3</sub> and THF/H<sub>2</sub>O (in 4:1 proportion) played crucial roles in the reaction. In contrast, this protocol employs a low palladium(II) complex loading and AgNO<sub>3</sub> as cocatalyst to obtain the homocoupled products in moderate to good yields.</p>