10.6084/m9.figshare.4503029.v1 Bo Chen Bo Chen Mengping Guo Mengping Guo Yongju Wen Yongju Wen Xiuli Shen Xiuli Shen Xiuling Zhou Xiuling Zhou Meiyun Lv Meiyun Lv Efficient P, O chelate palladium(II)/AgNO<sub>3</sub> cocatalyzed homocoupling of aromatic terminal alkynes in aqueous media under ambient atmosphere Taylor & Francis Group 2016 Aromatic terminal alkynes P,O chelate Pd(II) complex/AgNO3 cocatalyst homocoupling reaction 1,4-disubstituted-1,3-diynes 2016-12-29 16:12:04 Journal contribution https://tandf.figshare.com/articles/journal_contribution/Efficient_P_O_chelate_palladium_II_AgNO_sub_3_sub_cocatalyzed_homocoupling_of_aromatic_terminal_alkynes_in_aqueous_media_under_ambient_atmosphere/4503029 <p>A new and efficient protocol for the P, O chelate Pd(II)/AgNO<sub>3</sub> cocatalyzed oxidative homocoupling reaction of aromatic terminal alkynes in the synthesis of symmetrical 1,4-disubstituted-1,3-diynes was described in aqueous media under ambient atmosphere. The results showed that both NEt<sub>3</sub> and THF/H<sub>2</sub>O (in 4:1 proportion) played crucial roles in the reaction. In contrast, this protocol employs a low palladium(II) complex loading and AgNO<sub>3</sub> as cocatalyst to obtain the homocoupled products in moderate to good yields.</p>