Wu, Hai-Yan Sheng, Yu Kan, Xue-Qin Mou, Lin-Yun Hu, Qiu-Feng Li, Gan-Peng Three new xanthones from <i>Swertia bimaculata</i> and their anti-5<i>α</i>-reductase activity <p>Three new xanthones (<b>1</b>–<b>3</b>), together with five known ones (<b>4</b>–<b>8</b>), were isolated from whole herb of <i>Swertia bimaculata</i>. Their structures were established on the basis of detailed spectroscopic analysis (1D- and 2D-NMR, HRESIMS, UV, and IR) and comparison with data reported in the literature. New isolates were evaluated for their anti-5<i>α</i>-reductase activity. The results revealed that all new compounds showed weak activity with reductase inhibitions of 40.5 ± 2.8, 38.6 ± 2.5, and 48.9 ± 3.0%, respectively.</p> Gentianaceae;Swertia bimaculata;xanthones;anti-5α-reductase activity 2016-12-29
    https://tandf.figshare.com/articles/journal_contribution/Three_new_xanthones_from_i_Swertia_bimaculata_i_and_their_anti-5_i_i_-reductase_activity/4502753
10.6084/m9.figshare.4502753.v1