10.6084/m9.figshare.c.3646397_D1.v1
M. Brahimi-Horn
M.
Brahimi-Horn
Sandy Giuliano
Sandy
Giuliano
Estelle Saland
Estelle
Saland
Sandra Lacas-Gervais
Sandra
Lacas-Gervais
Tatiana Sheiko
Tatiana
Sheiko
Joffrey Pelletier
Joffrey
Pelletier
Isabelle Bourget
Isabelle
Bourget
Frédéric Bost
Frédéric
Bost
Chloé Féral
Chloé
Féral
Etienne Boulter
Etienne
Boulter
Michel Tauc
Michel
Tauc
Mircea Ivan
Mircea
Ivan
Barbara Garmy-Susini
Barbara
Garmy-Susini
Alexandra Popa
Alexandra
Popa
Bernard Mari
Bernard
Mari
Jean-Emmanuel Sarry
Jean-Emmanuel
Sarry
William Craigen
William
Craigen
Jacques Pouysségur
Jacques
Pouysségur
Nathalie Mazure
Nathalie
Mazure
Additional file 10: Figure S5. of Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation
Springer Nature
2015
presence
ebselen
absence
inflammation Glutathione peroxidase expression
reactive oxygen species generation
72 h
normoxia
GPX 7
Wt
MEF
Vdac 1 activates hypoxia-inducible factor
HIF -1α
tumor growth
2015-08-26 05:00:00
Journal contribution
https://springernature.figshare.com/articles/journal_contribution/Additional_file_10_Figure_S5_of_Knockout_of_Vdac1_activates_hypoxia-inducible_factor_through_reactive_oxygen_species_generation_and_induces_tumor_growth_by_promoting_metabolic_reprogramming_and_inflammation/4475123
Glutathione peroxidase expression and the effect of ebselen. (A) Immunofluorescence to GPX7 in Wt and Vdac1 −/− MEF in Nx or Hx for 72 h. (B) Immunoblotting for HIF-1α of Wt and Vdac1 −/− MEF in the absence or presence of ebselen in normoxia. (C) Proliferation of Wt and Vdac1 −/− MEF in the absence or presence of ebselen in normoxia. (D) Viability of Wt and Vdac1 −/− MEF in the absence or presence of ebselen in normoxia.