Additional file 5: Figure S3. of MDSINE: Microbial Dynamical Systems INference Engine for microbiome time-series analyses
Vanni Bucci
Belinda Tzen
Ning Li
Matt Simmons
Takeshi Tanoue
Elijah Bogart
Luxue Deng
Vladimir Yeliseyev
Mary Delaney
Qing Liu
Bernat Olle
Richard Stein
Kenya Honda
Lynn Bry
Georg Gerber
10.6084/m9.figshare.c.3640829_D8.v1
https://springernature.figshare.com/articles/journal_contribution/Additional_file_5_Figure_S3_of_MDSINE_Microbial_Dynamical_Systems_INference_Engine_for_microbiome_time-series_analyses/4456802
Experimental design for probiotic stability studies in gnotobiotic mice. Seven adult germ-free mice were gavaged with 13 Clostridia strains from the VE202 probiotic cocktail [24]. Five mice were maintained on a standard high-fiber diet for 5 weeks, after which mice were switched to a low-fiber diet for 2 weeks and then switched back to the high-fiber diet for another 2 weeks; an additional two mice were inoculated with the same strains but were not subjected to the low-fiber dietary perturbation. Fecal pellets were collected at days 1–21 (daily), 23, 25, 27, 29, 31, 33, 35–60 (daily), 62, 63, and 65 for the five mice receiving the low-fiber dietary perturbation and at days 1–21 (daily), 23, 25, 27, and 29 for the two mice not receiving the perturbation. (PDF 42 kb)
2016-06-03 05:00:00
low-fiber
VE
perturbation
MDSINE
13 Clostridia strains
adult germ-free mice
2 weeks
diet
microbiome time-series analyses
Microbial Dynamical Systems INference Engine
PDF 42 kb
probiotic stability studies