TY - DATA T1 - Additional file 6: of Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis PY - 2016/10/24 AU - Chrysoula Konstantinidou AU - Stavros Taraviras AU - Vassilis Pachnis UR - https://springernature.figshare.com/articles/figure/Additional_file_6_of_Geminin_prevents_DNA_damage_in_vagal_neural_crest_cells_to_ensure_normal_enteric_neurogenesis/4444427 DO - 10.6084/m9.figshare.c.3637328_D6.v1 L4 - https://ndownloader.figshare.com/files/7172183 KW - Apoptosis KW - Development KW - DNA damage KW - Enteric nervous system KW - Geminin KW - Neural crest N2 - Figure S5. Ablation of Gem from ENCCs does not affect their commitment to the neuronal and glial lineages. (A), Quantification of short-term cultured GFP+ ENCCs of control and Sox10CreER(i10)|Gem embryos, immunostained for GFP, Ki67, pH3, Sox10, BFABP, S100, Tuj1, HuC/D and processed for EdU labelling. Unpaired t-test, insignificant differences observed. (B–D), Relative quantitation of Sox10, Phox2b, Ret, HuC and BFABP transcript levels in the ENCCs of Sox10CreER(i10)|Gem embryos from the stomach, midgut and caecum-hindgut, respectively. Values were normalised to the levels of GFP. Multiple t-tests without correction, insignificant differences observed. (TIF 1381 kb) ER -