10.6084/m9.figshare.c.3636671_D7.v1
Daria Drobysheva
Daria
Drobysheva
Brittni Smith
Brittni
Smith
Maria McDowell
Maria
McDowell
Katrin Guillen
Katrin
Guillen
Huseyin Ekiz
Huseyin
Ekiz
Bryan Welm
Bryan
Welm
Additional file 5: Figure S5. of Transformation of enriched mammary cell populations with polyomavirus middle T antigen influences tumor subtype and metastatic potential
Springer Nature
2015
tumor histology
Molecularly basal tumors
Western blot quantification
SRC protein expression
ERK
t test
tumor groups
polyomavirus middle T antigen influences tumor subtype
population tumors
PyMT activity comparison
AKT
blot quantification
protein expression
TIFF 1046 kb
β- actin
2015-10-01 05:00:00
Figure
https://springernature.figshare.com/articles/figure/Additional_file_5_Figure_S5_of_Transformation_of_enriched_mammary_cell_populations_with_polyomavirus_middle_T_antigen_influences_tumor_subtype_and_metastatic_potential/4442267
PyMT activity comparison with tumor histology, molecular subtype, and metastasis. a Western blot quantification of relative ratio of pAKT to AKT, pERK to ERK, and pSRC to SRC protein expression in enriched population tumors segregated based on tumor histology and normalized to β-actin. No significant differences in protein expression were detected among tumor groups (t test, n = number of tumors). b Western blot quantification of relative ratio of pAKT to AKT, pERK to ERK, and pSRC to SRC protein expression in enriched population tumors segregated based on tumor molecular subtype and normalized to β-actin. Molecularly basal tumors exhibited significantly higher levels of pERK/ERK levels than luminal tumors (t test, p value shown, n = number of tumors). c Western blot quantification of relative ratio of pAKT to AKT, pERK to ERK, and pSRC to SRC protein expression in enriched population tumors segregated based on tumor metastasis and normalized to β-actin. No significant differences in protein expression were detected among tumor groups (t test, n = number of tumors). (TIFF 1046 kb)