%0 Online Multimedia %A Southworth, Thomas %A Plumb, Jonathan %A Gupta, Vandana %A Pearson, James %A Ramis, Isabel %A Lehner, Martin %A Miralpeix, Montserrat %A Singh, Dave %D 2016 %T Additional file 9: Figure S3. of Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients %U https://springernature.figshare.com/articles/presentation/Additional_file_9_Figure_S3_of_Anti-inflammatory_potential_of_PI3K_and_JAK_inhibitors_in_asthma_patients/4429880 %R 10.6084/m9.figshare.c.3632936_D8.v1 %2 https://ndownloader.figshare.com/files/7156514 %K Asthma %K Phosphatidylinositol 3-kinase delta %K JAK/STAT %K T-cell cytokines %K Bronchoscopy %X Effects of Dexamethasone, PIK-294 and tofacinib on IL-6 from TCR-stimulated BAL cells. BAL cells from asthma patients (n = 5) were treated with varying concentrations of dexamethasone with or without 100nM of tofacitinib for 1 h before being stimulated with antibodies against CD3 and CD28 to induce a TCR-specific response. IL-6 was measured by ELISA. Data is presented as mean +/− standard deviation. Drug effects were analysed by 1-way ANOVA: p = 0.22. (PPTX 89 kb) %I figshare