10.6084/m9.figshare.c.3632936_D8.v1 Thomas Southworth Thomas Southworth Jonathan Plumb Jonathan Plumb Vandana Gupta Vandana Gupta James Pearson James Pearson Isabel Ramis Isabel Ramis Martin Lehner Martin Lehner Montserrat Miralpeix Montserrat Miralpeix Dave Singh Dave Singh Additional file 9: Figure S3. of Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients Springer Nature 2016 Asthma Phosphatidylinositol 3-kinase delta JAK/STAT T-cell cytokines Bronchoscopy 2016-10-04 05:00:00 Presentation https://springernature.figshare.com/articles/presentation/Additional_file_9_Figure_S3_of_Anti-inflammatory_potential_of_PI3K_and_JAK_inhibitors_in_asthma_patients/4429880 Effects of Dexamethasone, PIK-294 and tofacinib on IL-6 from TCR-stimulated BAL cells. BAL cells from asthma patients (n = 5) were treated with varying concentrations of dexamethasone with or without 100nM of tofacitinib for 1 h before being stimulated with antibodies against CD3 and CD28 to induce a TCR-specific response. IL-6 was measured by ELISA. Data is presented as mean +/− standard deviation. Drug effects were analysed by 1-way ANOVA: p = 0.22. (PPTX 89 kb)