TY - DATA T1 - MOESM4 of Weight loss reduces basal-like breast cancer through kinome reprogramming PY - 2016/04/01 AU - Yuanyuan Qin AU - Sneha Sundaram AU - Luma Essaid AU - Xin Chen AU - Samantha Miller AU - Feng Yan AU - David Darr AU - Joseph Galanko AU - Stephanie Montgomery AU - Michael Major AU - Gary Johnson AU - Melissa Troester AU - Liza Makowski UR - https://springernature.figshare.com/articles/figure/MOESM4_of_Weight_loss_reduces_basal-like_breast_cancer_through_kinome_reprogramming/4422218 DO - 10.6084/m9.figshare.c.3630467_D2.v1 L4 - https://ndownloader.figshare.com/files/7148864 KW - Kinome KW - MAPK KW - AMPK obesity KW - Leptin KW - High fat diet KW - Adiposity KW - Body composition N2 - Additional file 4. Kinome analysis revealed dramatic regulation of kinases by HFD and diet-induced weight loss. a. HFD (60 %-fed) mammary gland kinase activity of greater than 1.5 or less than 0.5 fold compared to 10 %-fed is presented. b. Weight loss (60–10 %-fed) mammary gland kinase activity of greater than 1.25 or less than 0.5 fold compared to 10 %-fed is presented. In b, no error bar is present in pooled samples when kinases were down-regulated below level of detection and only 1 run detected activity. ER -