Additional file 3: Figure S3. of Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo
Leslie Calapre
Elin Gray
Sandrine Kurdykowski
Anthony David
Prue Hart
Pascal Descargues
Mel Ziman
10.6084/m9.figshare.c.3627287_D2.v1
https://springernature.figshare.com/articles/figure/Additional_file_3_Figure_S3_of_Heat-mediated_reduction_of_apoptosis_in_UVB-damaged_keratinocytes_in_vitro_and_in_human_skin_ex_vivo/4412702
Exposure to UVB plus heat induced a significant decrease in acetylated p53 levels in NHEK and in skin models. Immunohistochemical staining of CPD (red), p53-a382 or SIRT1-p (green) and DAPI (blue) in untreated or UVB and/or heat treated NHEK. Cells co-expressing p53-a382/CPD are also indicated by green arrows. Scale bar (white line) =100Â Îźm. (JPG 304 kb)
2016-05-26 05:00:00
Heat stress
UVB
Keratinocytes
Apoptosis
p53
DNA damage