%0 Figure %A Tornero, Daniel %A Posadas, Inmaculada %A Ceña, Valentín %D 2011 %T Lack of effect of Bcl-xL over expression on ionomycin-mediated increase in Ca2+ levels. %U https://plos.figshare.com/articles/figure/_Lack_of_effect_of_Bcl_x_L_over_expression_on_ionomycin_mediated_increase_in_Ca_2_levels_/439024 %R 10.1371/journal.pone.0020423.g002 %2 https://ndownloader.figshare.com/files/768644 %K ionomycin-mediated %X

a) Time-course of Ca2+ levels, expressed as percentage of maximum Ca2+ response, following ionomycin (2 µM; arrow) addition to SH-SY5Y/Neo (solid lines) and SH-SY5Y/Bcl-xL cells (dashed lines). Following an initial Ca2+ peak, a late Ca2+ increase occurs reaching a plateau that is taken as the maximum Ca2+ level for the neuron. b) Cytoplasmatic response to ionomycin treatment (2 µM) in SH-SY5Y/Neo (n = 10) and SH-SY5Y/Bcl-xL (n = 11) cells measured as the ratio of the early Ca2+ peak to the maximal ionomycin signal obtained during each individual experiment. Data represent mean ± S.E.M of the indicated number of experiments.

%I PLOS ONE