TY - DATA T1 - MD simulations of KIT cytoplasmic region in the auto-inhibited inactive form. PY - 2011/06/16 AU - Elodie Laine AU - Isaure Chauvot de Beauchêne AU - David Perahia AU - Christian Auclair AU - Luba Tchertanov UR - https://plos.figshare.com/articles/figure/_MD_simulations_of_KIT_cytoplasmic_region_in_the_auto_inhibited_inactive_form_/434677 DO - 10.1371/journal.pcbi.1002068.g002 L4 - https://ndownloader.figshare.com/files/764308 KW - simulations KW - cytoplasmic KW - auto-inhibited KW - inactive N2 - The RMS deviations (in Å) were calculated from MD simulations of full-length CR for wild-type KIT, WT547-935 (in blue), and D816V mutant, MU547-935 (in red), on the backbone atoms of (a) the whole CR, (b) N-lobe, (c) C-lobe, (d) A-loop and (e) JMR. The 50-ns simulations 1 and 2 of the wild-type (mutant, respectively) are shown by plain and dashed lines. The dashed grey vertical line drawn at 2 ns indicates the relaxation time. ER -