10.6084/m9.figshare.c.3598400_D6.v1 Henning Hofmann Henning Hofmann Bénédicte Vanwalscappel Bénédicte Vanwalscappel Nicolin Bloch Nicolin Bloch Nathaniel Landau Nathaniel Landau MOESM1 of TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes Springer Nature 2016 TLR7/8 HIV restriction R848 Monocytes Restriction factor 2016-12-01 05:00:00 Presentation https://springernature.figshare.com/articles/presentation/MOESM1_of_TLR7_8_agonist_induces_a_post-entry_SAMHD1-independent_block_to_HIV-1_infection_of_monocytes/4325066 Additional file 1. R848 blocks Vpx-containing HIV-1 infection from multiple donors. PBMC from healthy donors were pretreated with 10 μM R848 (blue squares) for 24 h and then infected with HIV1 X+ luciferase reporter virus. Infectivity was measured 72 h post infection. The data are from independent experiments with 18 different donors (**p = 0.0011).