10.6084/m9.figshare.c.3595850_D4.v1 Milos Ikonomovic Milos Ikonomovic Chris Buckley Chris Buckley Kerstin Heurling Kerstin Heurling Paul Sherwin Paul Sherwin Paul Jones Paul Jones Michelle Zanette Michelle Zanette Chester Mathis Chester Mathis William Klunk William Klunk Aruna Chakrabarty Aruna Chakrabarty James Ironside James Ironside Azzam Ismail Azzam Ismail Colin Smith Colin Smith Dietmar Thal Dietmar Thal Thomas Beach Thomas Beach Gill Farrar Gill Farrar Adrian Smith Adrian Smith Additional file 3: of Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection Springer Nature 2016 Flutemetamol PET Amyloid Alzheimer’s disease Neuropathology (4-6 allowed) 2016-12-12 05:00:00 Journal contribution https://springernature.figshare.com/articles/journal_contribution/Additional_file_3_of_Post-mortem_histopathology_underlying_-amyloid_PET_imaging_following_flutemetamol_F_18_injection/4316747 ROC Analysis - Dichotomised BIE (majority read) vs categorical neuropathology. Comparison of the 4 histopathological criteria of assigning abnormal amyloid against a dichotomised (Abnormal/Normal) majority blinded PET Image evaluation. The 4 criteria shown are CERAD [43], National Institutes of Ageing – Reagan Institute AD diagnosis [26], National Institutes of Ageing – Alzheimer’s Association AD diagnosis [25] and Amyloid phase (Phase 3 or greater) [58]. (DOC 201 kb)