TY - DATA T1 - ERG response from untreated Line 1 P23H-R transgenic animals (nā€Š=ā€Š5, pattern or dashed lines in all panels) and those treated with curcumin at 100 mg/kg body weight dose (nā€Š=ā€Š13. Solid lines/bars in all panels). PY - 2013/02/20 AU - Vidyullatha Vasireddy AU - Venkata R. M. Chavali AU - Victory T. Joseph AU - Rajendra Kadam AU - Jonathan H. Lin AU - Jeffrey A. Jamison AU - Uday B. Kompella AU - Geereddy Bhanuprakash Reddy AU - Radha Ayyagari UR - https://plos.figshare.com/articles/figure/_ERG_response_from_untreated_Line_1_P23H_R_transgenic_animals_n_8202_8202_5_pattern_or_dashed_lines_in_all_panels_and_those_treated_with_curcumin_at_100_mg_kg_body_weight_dose_n_8202_8202_13_Solid_lines_bars_in_all_panels_/431216 DO - 10.1371/journal.pone.0021193.g004 L4 - https://ndownloader.figshare.com/files/760862 KW - untreated KW - p23h-r KW - transgenic KW - animals KW - dashed KW - lines KW - treated KW - curcumin KW - 100 N2 - (A) The treated animals have improved scotopic A and B-wave amplitudes and improved (B) photopic B-wave amplitudes across all intensities compared to untreated rats. (C) The amplitude latencies remain unchanged in untreated rats suggesting no appreciable change in photoreceptor function. While A and B-wave amplitudes are clearly improved in the treated animals, a statistically significant (students t-test p<0.05) difference is observed in the maximum scotopic and photopic B-wave amplitudes of treated rats when compared to untreated P23H-R transgenic controls (D). ER -