%0 Figure %A Vasireddy, Vidyullatha %A R. M. Chavali, Venkata %A T. Joseph, Victory %A Kadam, Rajendra %A H. Lin, Jonathan %A A. Jamison, Jeffrey %A Kompella, Uday B. %A Bhanuprakash Reddy, Geereddy %A Ayyagari, Radha %D 2013 %T ERG response from untreated Line 1 P23H-R transgenic animals (nā€Š=ā€Š5, pattern or dashed lines in all panels) and those treated with curcumin at 100 mg/kg body weight dose (nā€Š=ā€Š13. Solid lines/bars in all panels). %U https://plos.figshare.com/articles/figure/_ERG_response_from_untreated_Line_1_P23H_R_transgenic_animals_n_8202_8202_5_pattern_or_dashed_lines_in_all_panels_and_those_treated_with_curcumin_at_100_mg_kg_body_weight_dose_n_8202_8202_13_Solid_lines_bars_in_all_panels_/431216 %R 10.1371/journal.pone.0021193.g004 %2 https://ndownloader.figshare.com/files/760862 %K untreated %K p23h-r %K transgenic %K animals %K dashed %K lines %K treated %K curcumin %K 100 %X

(A) The treated animals have improved scotopic A and B-wave amplitudes and improved (B) photopic B-wave amplitudes across all intensities compared to untreated rats. (C) The amplitude latencies remain unchanged in untreated rats suggesting no appreciable change in photoreceptor function. While A and B-wave amplitudes are clearly improved in the treated animals, a statistically significant (students t-test p<0.05) difference is observed in the maximum scotopic and photopic B-wave amplitudes of treated rats when compared to untreated P23H-R transgenic controls (D).

%I PLOS ONE