10.1021/acs.orglett.6b03300.s001
Yunhe Jin
Yunhe
Jin
Haijun Yang
Haijun
Yang
Hua Fu
Hua
Fu
Thiophenol-Catalyzed Visible-Light Photoredox Decarboxylative
Couplings of <i>N</i>‑(Acetoxy)phthalimides
American Chemical Society
2016
visible-light photoredox reactions
representative decarboxylative examples
room temperature
Thiophenol-Catalyzed Visible-Light Photoredox Decarboxylative Couplings
visible-light photoredox transformation
visible-light photoredox decarboxylative couplings
2016-12-07 18:54:15
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Thiophenol-Catalyzed_Visible-Light_Photoredox_Decarboxylative_Couplings_of_i_N_i_Acetoxy_phthalimides/4292282
We have developed
visible-light photoredox decarboxylative couplings
of <i>N</i>-(acetoxy)phthalimides without an added
photocatalyst in which simple and commercially available thiophenols
are used as the effective organocatalysts, and 4-(trifluoromethyl)thiophenol
shows optimal catalytic activity. Three representative decarboxylative
examples were chosen including one amination and two C–C bond
couplings to confirm efficacy of the visible-light photoredox reactions,
and the results exhibited that they performed very well at room temperature.
The interesting discovery should provide a novel and environmentally
friendly strategy for visible-light photoredox transformation of organic
molecules.