10.1371/journal.pone.0023144.g002
Rute B. Marques
Rute
B. Marques
Natasja F. Dits
Natasja
F. Dits
Sigrun Erkens-Schulze
Sigrun
Erkens-Schulze
Wilfred F. J. van IJcken
Wilfred
F. J. van IJcken
Wytske M. van Weerden
Wytske
M. van Weerden
Guido Jenster
Guido
Jenster
Expression profile of androgen-responsive genes in PC346 cells linked to publicly available databases on AR transcriptional regulation.
Public Library of Science
2011
androgen-responsive
genes
pc346
cells
linked
databases
ar
transcriptional
2011-08-04 02:32:03
Figure
https://plos.figshare.com/articles/figure/_Expression_profile_of_androgen_responsive_genes_in_PC346_cells_linked_to_publicly_available_databases_on_AR_transcriptional_regulation_/419123
<p>On the left side, PC346C, PC346Flu1 and PC34Flu2 were exposed to 1 nM R1881 or 1 µM OH-flutamide for 4, 8 and 16h, whereas PC346DCC was stimulated with 1 nM R1881 only. On the right side, our gene signature was assessed in the databases from DePrimo <i>et al.</i>, Nelson <i>et al.</i>, Nickols <i>et al.</i>, Wang <i>et al.</i> and Hendriksen <i>et al.</i> (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0023144#pone-0023144-t007" target="_blank">Table 7</a> for database details). Heat-map is presented for the 2log expression ratio between hormone-treated samples and respective time-matched vehicle controls. Red and green colors represent induction and repression, respectively, whereas black indicates no regulation. Grey squares indicate missing data due to low expression, poor data quality or absence of probes for the respective transcript in the array platform used for the study.</p>