Supplementary Material for: The Prevalence and Long-Term Outcomes of Extreme Right versus Extreme Left Ventricular Hypertrophic Cardiomyopathy Guo X. Fan C. Wang H. Zhao S. Duan F. Wang Z. Yan L. Yang Y. An S. Li Y. 10.6084/m9.figshare.4056582.v1 https://karger.figshare.com/articles/media/Supplementary_Material_for_The_Prevalence_and_Long-Term_Outcomes_of_Extreme_Right_versus_Extreme_Left_Ventricular_Hypertrophic_Cardiomyopathy/4056582 <br><strong><em>Objectives:</em></strong> Extreme left ventricular hypertrophy (LVH) is a known risk factor for sudden cardiac death in hypertrophic cardiomyopathy (HCM). Extreme right ventricular hypertrophy (RVH) is rare, and whether it is linked to a poor outcome is unknown. This study was designed to investigate differences between HCM patients with extreme RVH and those with extreme LVH. <b><i>Methods:</i></b> Among 2,413 HCM patients, 31 with extreme RVH (maximum right ventricular wall thickness ≥10 mm) and 194 with extreme LVH (maximum left ventricular wall thickness ≥30 mm) were investigated. The main clinical features and natural history were compared between the 2 groups. <b><i>Results:</i></b> The prevalence of extreme RVH and extreme LVH was 1.3 and 8.0%, respectively. Patients with extreme RVH tended to be younger and female (p < 0.01). Cardiovascular-related mortality and morbidity within 10 years were significantly greater in the extreme RVH group (p < 0.05). Multivariate analysis demonstrated 3 independent predictors for cardiovascular mortality - extreme RVH, left ventricular end-diastolic dimension ≥50 mm, and age ≤18 years at baseline - and 2 for morbidity - extreme RVH and presyncope. <b><i>Conclusions:</i></b> Compared with extreme LVH, extreme RVH was quite uncommon in HCM and had a worse prognosis. A right ventricle examination should be performed in routine HCM evaluation. 2016-10-25 09:59:35 Right ventricular hypertrophy Left ventricular hypertrophy Hypertrophic cardiomyopathy Outcomes