Effect of genipin on KSHV infection. Miyeon Cho Seok Won Jung Soomin Lee Kuwon Son Gyu Hwan Park Jong-Wha Jung Yu Su Shin Taegun Seo Hyosun Cho Hyojeung Kang 10.1371/journal.pone.0163693.g006 https://plos.figshare.com/articles/figure/Effect_of_genipin_on_KSHV_infection_/4030398 <p>Effects of genipin on KSHV infection to iSLK-puro cells were determined by KSHV infection assay. (A) GFP foci formed on 72 μM genipin treated iSLK-puro cells that were infected for 72 h with KSHV virions (low titer) harvested from iSLK-BAC16 cells treated with only sodium butyrate. (B) A graph showing the effect of genipin treatment at 72 μM on the low titer KSHV infection to iSLK-puro cells. (C) GFP foci formed on 72 μM genipin treated iSLK-puro cells that were infected for 72 h with KSHV virions (high titer) harvested from iSLK-BAC16 cells treated with both sodium butyrate and doxycyclin. (D) A graph showing the effect of genipin treatment at 72 μM on the high titer KSHV infection to iSLK-puro cells.</p> 2016-10-13 17:34:52 KSHV intracellular copy numbers KSHV life cycle chromosomes protein 3 KSHV lytic replication CTCF RNA RTA genipin treatment KSHV extracellular copy numbers DNMT KSHV LANA transcripts KSHV infection AIDS SMC DNA concentration 72.5 μ M iSLK-BAC 16 KSHV infection system KSHV latency control region 49.5 μ M chromatin immunoprecipitation assay iSLK-BAC 16 cells