10.1371/journal.pone.0163693.g006 Miyeon Cho Miyeon Cho Seok Won Jung Seok Won Jung Soomin Lee Soomin Lee Kuwon Son Kuwon Son Gyu Hwan Park Gyu Hwan Park Jong-Wha Jung Jong-Wha Jung Yu Su Shin Yu Su Shin Taegun Seo Taegun Seo Hyosun Cho Hyosun Cho Hyojeung Kang Hyojeung Kang Effect of genipin on KSHV infection. Public Library of Science 2016 KSHV intracellular copy numbers KSHV life cycle chromosomes protein 3 KSHV lytic replication CTCF RNA RTA genipin treatment KSHV extracellular copy numbers DNMT KSHV LANA transcripts KSHV infection AIDS SMC DNA concentration 72.5 μ M iSLK-BAC 16 KSHV infection system KSHV latency control region 49.5 μ M chromatin immunoprecipitation assay iSLK-BAC 16 cells 2016-10-13 17:34:52 Figure https://plos.figshare.com/articles/figure/Effect_of_genipin_on_KSHV_infection_/4030398 <p>Effects of genipin on KSHV infection to iSLK-puro cells were determined by KSHV infection assay. (A) GFP foci formed on 72 μM genipin treated iSLK-puro cells that were infected for 72 h with KSHV virions (low titer) harvested from iSLK-BAC16 cells treated with only sodium butyrate. (B) A graph showing the effect of genipin treatment at 72 μM on the low titer KSHV infection to iSLK-puro cells. (C) GFP foci formed on 72 μM genipin treated iSLK-puro cells that were infected for 72 h with KSHV virions (high titer) harvested from iSLK-BAC16 cells treated with both sodium butyrate and doxycyclin. (D) A graph showing the effect of genipin treatment at 72 μM on the high titer KSHV infection to iSLK-puro cells.</p>