Payen, Celia B. Sunshine, Anna T. Ong, Giang Pogachar, Jamie L. Zhao, Wei J. Dunham, Maitreya Alternative accessible evolutionary paths. <p><b>(A)</b> The fitness of beneficial mutations found (F) in Evolve and Resequence studies is significantly higher than the fitness of beneficial mutations not found (NF) in sulfate-limitation but not in glucose-limitation. The significance of the difference between the two boxplots for each condition was estimated using a Wilcoxon-ranked test. (<b>B)</b> Each point represents the fitness of a strain and the proportion of Evolve and Resequence samples with the corresponding gene mutated. <i>SUL1</i> dominates the fitness and mutational spectrum. Several mutations have a high fitness but have never been detected in Evolve and Resequence studies and might correspond to potential drivers of adaptation.</p> nutrient-limited conditions;sulfate-limited condition;mutation;high-affinity sulfate transporter;fitness effects;Evolved Yeast Populations High-throughput sequencing 2016-10-11
    https://plos.figshare.com/articles/figure/Alternative_accessible_evolutionary_paths_/4012158
10.1371/journal.pgen.1006339.g005