10.1371/journal.pgen.1006339.g005
Celia Payen
Celia
Payen
Anna B. Sunshine
Anna
B. Sunshine
Giang T. Ong
Giang
T. Ong
Jamie L. Pogachar
Jamie L.
Pogachar
Wei Zhao
Wei
Zhao
Maitreya J. Dunham
Maitreya
J. Dunham
Alternative accessible evolutionary paths.
Public Library of Science
2016
nutrient-limited conditions
sulfate-limited condition
mutation
high-affinity sulfate transporter
fitness effects
Evolved Yeast Populations High-throughput sequencing
2016-10-11 17:38:02
Figure
https://plos.figshare.com/articles/figure/Alternative_accessible_evolutionary_paths_/4012158
<p><b>(A)</b> The fitness of beneficial mutations found (F) in Evolve and Resequence studies is significantly higher than the fitness of beneficial mutations not found (NF) in sulfate-limitation but not in glucose-limitation. The significance of the difference between the two boxplots for each condition was estimated using a Wilcoxon-ranked test. (<b>B)</b> Each point represents the fitness of a strain and the proportion of Evolve and Resequence samples with the corresponding gene mutated. <i>SUL1</i> dominates the fitness and mutational spectrum. Several mutations have a high fitness but have never been detected in Evolve and Resequence studies and might correspond to potential drivers of adaptation.</p>