10.1371/journal.pgen.1006339.g003
Celia Payen
Celia
Payen
Anna B. Sunshine
Anna
B. Sunshine
Giang T. Ong
Giang
T. Ong
Jamie L. Pogachar
Jamie L.
Pogachar
Wei Zhao
Wei
Zhao
Maitreya J. Dunham
Maitreya
J. Dunham
Recurrently mutated genes reveal how evolution is constrained.
Public Library of Science
2016
nutrient-limited conditions
sulfate-limited condition
mutation
high-affinity sulfate transporter
fitness effects
Evolved Yeast Populations High-throughput sequencing
2016-10-11 17:38:02
Figure
https://plos.figshare.com/articles/figure/Recurrently_mutated_genes_reveal_how_evolution_is_constrained_/4012152
<p>(<b>A</b>) Repeatability of adaptation and parallelism at the gene level. Genes were classified by the number of mutations detected during Evolve and Resequence studies: 154 genes were mutated in more than one sample; 48 genes with recurrent mutations were mutated in more than one condition (small panel). (<b>B</b>) Enrichment of recurrently mutated genes with high-impact mutations compared with genes mutated in only one sample. Enrichment is not observed for moderate or low impact mutations, or modifiers. Error bars are 95% CIs.</p>