The mGluR5-receptor antagonist MPEP attenuates elevated repetitive behaviors in mice exposed to valproic acid (VPA) <i>in utero.</i> Mili V. Mehta Michael J. Gandal Steven J. Siegel 10.1371/journal.pone.0026077.g001 https://plos.figshare.com/articles/figure/_The_mGluR5_receptor_antagonist_MPEP_attenuates_elevated_repetitive_behaviors_in_mice_exposed_to_valproic_acid_VPA_in_utero_/396514 <p>(<b>A</b>) Repetitive self-grooming was measured over 10 minutes in mice exposed to prenatal saline (SAL) or VPA. (<b>B</b>) Repetitive marble burying behavior was measured for both groups after a 30 minute testing session. Across both assays, VPA-exposed mice demonstrated elevated stereotyped, repetitive behaviors that were significantly reduced by MPEP. Figures show mean ± S.E.M., (*<i>p</i><0.05, **<i>p</i><0.01).</p> 2013-02-20 13:56:26 mglur5-receptor antagonist mpep attenuates elevated repetitive behaviors mice exposed valproic