TY - DATA T1 - BRCA1 Deficiency Score (BDS). PY - 2016/04/14 AU - Aruna Korlimarla AU - Jyothi S. Prabhu AU - Jose Remacle AU - Savitha Rajarajan AU - Uma Raja AU - Anupama C. E. AU - B. S. Srinath AU - Suraj Manjunath AU - Gopinath K. S. AU - Marjorrie Correa AU - Prasad M. S. N. AU - T. S. Sridhar UR - https://plos.figshare.com/articles/figure/BRCA1_Deficiency_Score_BDS_/3948609 DO - 10.1371/journal.pone.0153113.g007 L4 - https://ndownloader.figshare.com/files/6175488 KW - FFPE Tumor Samples KW - 112 Hormone receptor KW - TNBC KW - BRCA 1 protein KW - HR KW - BRCA 1 Deficiency KW - breast cancer tumor specimens KW - MS 110 antibody KW - MIRNA KW - BDS KW - PCR KW - HER KW - BRCA 1 deficiency KW - repressor ID 4 KW - germ-line BRCA 1-mutated breast cancers KW - repressors ID 4 KW - BRCA 1 KW - Breast Cancer Purpose N2 - BRCA1 Deficiency Score (BDS): Amalgamated scores range from a low of 0 to a high of 3. Scores of 0 and 1 are almost exclusively seen in TNBCs. Scores of 2 and 3 were seen in both HR+HER2- as well as TNBCs. 23/27 HR+HER2- tumors scored adequate on all measures and hence had a score of 3. This method of selection classified 40% of TNBCs being BRCA1 deficient and only 3% of HR+HER2-ve to be BRCA1 deficient. ER -