TY - DATA T1 - No difference in NPC death 24 h after discontinuation of propofol treatment. PY - 2016/07/05 AU - Arvind Palanisamy AU - Matthew B. Friese AU - Emily Cotran AU - Ludde Moller AU - Justin D. Boyd AU - Gregory Crosby AU - Deborah J. Culley UR - https://plos.figshare.com/articles/figure/No_difference_in_NPC_death_24_h_after_discontinuation_of_propofol_treatment_/3913143 DO - 10.1371/journal.pone.0158058.g004 L4 - https://ndownloader.figshare.com/files/6126351 KW - NPC proliferation KW - cell pool pool KW - baseline 24 h KW - Rat Neural Progenitor Cells KW - Vitro Neurocognitive dysfunction KW - propofol KW - propidium iodine staining KW - Propofol Transiently Impairs Proliferation KW - caspase -3 immunocytochemistry KW - concentration KW - progenitor cell biology KW - 24 hours KW - ICU KW - exposure KW - cell death KW - day 14 Sprague-Dawley rat pups N2 - A bar graph showing the proportion of dead NPCs in wells treated with either 2.5 or 5 μg/mL of propofol, 24 h after discontinuation of treatment as noted. Cell death was quantified with PI staining. There were no differences in NPC death at both concentrations compared to control treatment 24 h after discontinuation of propofol. Data are presented as mean ± S.E.M and expressed as percent of the control value (N = 3 per condition; P = 0.52 and 0.45 for the 4 and 24 h treatment groups, respectively, with 1-way ANOVA). ER -