%0 Figure %A Kohler, Christian %A J. Dunachie, Susanna %A Müller, Elke %A Kohler, Anne %A Jenjaroen, Kemajittra %A Teparrukkul, Prapit %A Baier, Vico %A Ehricht, Ralf %A Steinmetz, Ivo %D 2016 %T Development of signal intensities of grouped antigens inducing a long-term antibody response (A) and a short-term antibody response (B). %U https://plos.figshare.com/articles/figure/Development_of_signal_intensities_of_grouped_antigens_inducing_a_long-term_antibody_response_A_and_a_short-term_antibody_response_B_/3899520 %R 10.1371/journal.pntd.0004847.g005 %2 https://ndownloader.figshare.com/files/6108351 %K Direct pathogen detection %K IHA %K Protein Microarray Approach Background %K bacterium Burkholderia pseudomallei causes %K melioidosis patients %K antibody %K 52 weeks post-admission %K protein array %K sera %K Sensitive Multiplex Detection %X

Sera of individual patients (n = 36) were drawn upon admission (week 0 p.a.), 12 and 52 weeks p.a. Two graphs per antigen are shown. Left: the mean signal intensity per serum. Right: number of sera recognizing the respective antigen. Figures include only data of antigens found to be significantly recognized by melioidosis-positive sera. Statistical analyses were performed using repeated-measures ANOVA followed by Bonferroni's Multiple Comparison test comparing signal intensities measured in sera of week 0, 12 and 52 p.a. (*p<0.05; **p<0.01; ***p<0.001)

%I PLOS Neglected Tropical Diseases