%0 Figure %A Zigler, J. Samuel %A A. Hodgkinson, Colin %A Wright, Megan %A Klise, Andrew %A Sundin, Olof %A W. Broman, Karl %A Hejtmancik, Fielding %A Huang, Hao %A Patek, Bonnie %A Sergeev, Yuri %A Hose, Stacey %A Brayton, Cory %A Xaiodong, Jiao %A Vasquez, David %A Maragakis, Nicholas %A Mori, Susumu %A Goldman, David %A Hoke, Ahmet %A Sinha, Debasish %D 2016 %T Appearance of frogleg homozygous rat at 20 days of age. %U https://plos.figshare.com/articles/figure/Appearance_of_i_frogleg_i_homozygous_rat_at_20_days_of_age_/3877287 %R 10.1371/journal.pone.0160447.g004 %2 https://ndownloader.figshare.com/files/6078294 %K Spontaneous Missense Mutation %K D 1Rat %K mutation %K report novel data %K BCKDH %K rat chromosome 1 %K BCAA %K limb %K E 1α subunit %K Bckdk knockout mouse %K Branched Chain Keto %K genome sequencing data %K branched-chain alpha-keto dehydrogenase kinase %K BCKDK phosphorylates Ser 293 %K frogleg phenotype shares %X

The animal on the left shows the typical appearance of the frogleg pup, relative to a non-frogleg littermate on the right. Note the small size, the thin, rough coat, and the abnormal rotation of the hind limbs of the affected animal.

%I PLOS ONE