%0 Figure %A Fu, Yan %A Chryssafidis, Andreas L. %A A. Browne, John %A O'Sullivan, Jack %A A. McGettigan, Paul %A Mulcahy, Grace %D 2016 %T Production of nitric oxide in macrophages. %U https://plos.figshare.com/articles/figure/Production_of_nitric_oxide_in_macrophages_/3857595 %R 10.1371/journal.pntd.0005015.g005 %2 https://ndownloader.figshare.com/files/6044073 %K hepatica infection %K vivo study %K mechanisms underpinning %K ovine PBMC %K DEGS %K gene expression changes %K livestock farming %K food-borne zoonotic agent %K novel information %K Transcriptomic Study %K Several transcriptional regulators %K Potential mechanisms %K control strategies %K miR 155-5p %K Signaling %K TLR %K Nitric Oxide %K transcriptomic analysis %K Ingenuity Pathway Analysis %K Fasciola hepatica Infection Background Fasciola hepatica %K IL 18 %K IL 12 %K TGF %K Ovine Immune Responses %K response %K immune-associated pathways %X

This pathway is represented with gene expression (log2 fold-change) values overlaid. Red shading indicates increased expression in PBMCs at T2 compared to T1. Green shading indicates decreased expression in PBMCs at T2 compared to T1. Color intensity indicates expression level. White and grey shading indicates not significantly differentially expressed and filtered out due to low expression, respectively.

%I PLOS Neglected Tropical Diseases