TY - DATA T1 - The temporally controlled expression of Drongo, the fruit fly homolog of AGFG1, is achieved in female germline cells via P-bodies and its localization requires functional Rab11 PY - 2016/09/21 AU - Irina E. Catrina AU - Livia V. Bayer AU - Giussepe Yanez AU - John M. McLaughlin AU - Kornelia Malaczek AU - Ekaterina Bagaeva AU - Salvatore A. E. Marras AU - Diana P. Bratu UR - https://tandf.figshare.com/articles/dataset/The_temporally_controlled_expression_of_Drongo_the_fruit_fly_homolog_of_AGFG1_is_achieved_in_female_germline_cells_via_P-bodies_and_its_localization_requires_functional_Rab11/3846555 DO - 10.6084/m9.figshare.3846555.v1 L4 - https://ndownloader.figshare.com/files/6014184 L4 - https://ndownloader.figshare.com/files/6014187 L4 - https://ndownloader.figshare.com/files/6014190 L4 - https://ndownloader.figshare.com/files/6014193 L4 - https://ndownloader.figshare.com/files/6014196 L4 - https://ndownloader.figshare.com/files/6014199 L4 - https://ndownloader.figshare.com/files/6014202 L4 - https://ndownloader.figshare.com/files/6014205 L4 - https://ndownloader.figshare.com/files/6014208 KW - AGFG1 KW - cytoskeleton KW - Drongo KW - Drosophila KW - HIV-1 KW - Influenza A KW - Rab11 N2 - To achieve proper RNA transport and localization, RNA viruses exploit cellular vesicular trafficking pathways. AGFG1, a host protein essential for HIV-1 and Influenza A replication, has been shown to mediate release of intron-containing viral RNAs from the perinuclear region. It is still unknown what its precise role in this release is, or whether AGFG1 also participates in cytoplasmic transport. We report for the first time the expression patterns during oogenesis for Drongo, the fruit fly homolog of AGFG1. We find that temporally controlled Drongo expression is achieved by translational repression of drongo mRNA within P-bodies. Here we show a first link between the recycling endosome pathway and Drongo, and find that proper Drongo localization at the oocyte's cortex during mid-oogenesis requires functional Rab11. ER -