10.6084/m9.figshare.3839706.v1 Noronha V. Noronha V. Joshi A. Joshi A. Muddu V.K. Muddu V.K. Maruti Patil V. Maruti Patil V. Prabhash K. Prabhash K. Supplementary Material for: Cabazitaxel for Metastatic Castration-Resistant Prostate Cancer: Retrospective Data Analysis from an Indian Centre Karger Publishers 2016 Cabazitaxel Prostate-specific antigen Disease-free survival Neutropenia Leucopenia 2016-09-19 06:43:48 Figure https://karger.figshare.com/articles/figure/Supplementary_Material_for_Cabazitaxel_for_Metastatic_Castration-Resistant_Prostate_Cancer_Retrospective_Data_Analysis_from_an_Indian_Centre/3839706 <i>Objective:</i> To determine the efficacy and safety of cabazitaxel in metastatic castration-resistant prostate cancer (mCRPC) patients from the named patient programme (NPP) at our centre. <i>Methods:</i> mCRPC patients who progressed on docetaxel were given cabazitaxel intravenously every 3 weeks until disease progression or unacceptable toxicity occurred. Overall survival, progression-free survival, prostate-specific antigen response, quality of life (QOL) changes, and safety were reported. <i>Results:</i> Nine men received cabazitaxel (median: 7 cycles; range: 1–27) under the NPP and were followed until death. Median survival was 14.07 months (1.07–23.80) and progression-free survival was 2.67 months (1.07–20.27). QOL was stable for most patients. Common adverse events (grade ≥3) were neutropenia (n = 8), anaemia (n = 4), and leucopenia (n = 4). <i>Conclusion:</i> These data from 9 patients are consistent with the results reported in the TROPIC study with a manageable safety profile.