Xu, Dawei Zhao, Wei Zhu, Xinhui Fan, Jianbo Cui, Shengyu Sun, Yuyu Chen, Xiang Liu, Wei Cui, Zhi-ming OSU53 activates AMPK in human osteoblastic cells. <p>Human osteoblastic OB-6 cells were treated with or without OSU53 (10 μM) for two hours, expression of listed proteins was tested by Western blots (A). p-ACC level (vs. regular ACC) was quantified (B). “Ctrl” stands for untreated control group (Same for all figures). Experiments in this figure were repeated three times, and similar results were obtained. *<i>p</i><0.05 vs. “Ctrl” group (B).</p> Dex-induced osteoblastic OB -6 cell death;OSU 53-induced AMPK activation;Dex-treated osteoblastic cells;OSU 53;novel AMPK activator;alleviated Dex-induced oxidative stress;172A;Activating AMPK Signaling Excessive dexamethasone;OB -6 cells;OSU 53-induced actions;OSU 53 Rescues Human OB -6 Osteoblastic Cells;NADPH;OB -6 osteoblastic cells;application causes osteoblast cell death;nicotinamide adenine dinucleotide phosphate;OB -6 cell protection;OSU 53. OSU 53;AMP-activated protein kinase 2016-09-15
    https://plos.figshare.com/articles/figure/OSU53_activates_AMPK_in_human_osteoblastic_cells_/3836379
10.1371/journal.pone.0162694.g001