OSU53 activates AMPK in human osteoblastic cells. Dawei Xu Wei Zhao Xinhui Zhu Jianbo Fan Shengyu Cui Yuyu Sun Xiang Chen Wei Liu Zhi-ming Cui 10.1371/journal.pone.0162694.g001 https://plos.figshare.com/articles/figure/OSU53_activates_AMPK_in_human_osteoblastic_cells_/3836379 <p>Human osteoblastic OB-6 cells were treated with or without OSU53 (10 μM) for two hours, expression of listed proteins was tested by Western blots (A). p-ACC level (vs. regular ACC) was quantified (B). “Ctrl” stands for untreated control group (Same for all figures). Experiments in this figure were repeated three times, and similar results were obtained. *<i>p</i><0.05 vs. “Ctrl” group (B).</p> 2016-09-15 17:49:48 Dex-induced osteoblastic OB -6 cell death OSU 53-induced AMPK activation Dex-treated osteoblastic cells OSU 53 novel AMPK activator alleviated Dex-induced oxidative stress 172A Activating AMPK Signaling Excessive dexamethasone OB -6 cells OSU 53-induced actions OSU 53 Rescues Human OB -6 Osteoblastic Cells NADPH OB -6 osteoblastic cells application causes osteoblast cell death nicotinamide adenine dinucleotide phosphate OB -6 cell protection OSU 53. OSU 53 AMP-activated protein kinase