%0 Figure %A Krishna, Shyam %A Ray, Aurélie %A K. Dubey, Shiv %A Larrouy-Maumus, Gérald %A Chalut, Christian %A Castanier, Romain %A Noguera, Audrey %A Gilleron, Martine %A Puzo, Germain %A Vercellone, Alain %A Nampoothiri, K. Madhavan %A Nigou, Jérôme %D 2011 %T Lipoglycan increased production is associated with an enhancement of innate immune signaling. %U https://plos.figshare.com/articles/figure/_Lipoglycan_increased_production_is_associated_with_an_enhancement_of_innate_immune_signaling_/378286 %R 10.1371/journal.pone.0028476.g004 %2 https://ndownloader.figshare.com/files/707945 %K enhancement %K innate %X

A, B, E, F) NF-κB activation in HEK (A, E) and THP-1 (B, F) cells. C, D, G) IL-8 production by THP-1 (C, G) and human monocyte-derived dendritic (D) cells. Cells were incubated with bacteria at MOI of 1. In F and G, cells were pre-incubated for 30 min at 37°C before bacteria addition with various antibodies, anti-TLR2 and isotype controls, at a concentration of 5 µg/ml. The results are mean ± SD of triplicate wells and are representative of at least three separate experiments using independent bacterial cultures and different MOI. *, P<0.05; **, P<0.01; ***, P<0.001; ns, not significant. In A, B, C and D), P value is given vs pMV. n.i., not induced.

%I PLOS ONE