TY - DATA T1 - One-Step Synthesis of Spiropyridines, a Novel Class of C2-Symmetric Chiral Ligands, by Cobalt(I)-Catalyzed [2 + 2 + 2] Cycloadditions between Bis-Alkynenitriles and Alkynes† PY - 1999/12/09 AU - Jesús A. Varela AU - Luis Castedo AU - Carlos Saá UR - https://acs.figshare.com/articles/journal_contribution/One-Step_Synthesis_of_Spiropyridines_a_Novel_Class_of_i_C_i_sub_2_sub_-Symmetric_Chiral_Ligands_by_Cobalt_I_-Catalyzed_2_2_2_Cycloadditions_between_Bis-Alkynenitriles_and_Alkynes_sup_sup_/3761364 DO - 10.1021/ol991195m.s001 L4 - https://ndownloader.figshare.com/files/5868657 KW - cocyclization KW - C 2 KW - alkyne KW - synthesis KW - method KW - series KW - Synthesi KW - Spiropyridine KW - Alkyne KW - spyropyridine KW - Co KW - acyclic KW - precursor KW - ligand KW - yield KW - Cobalt KW - Cycloaddition KW - Symmetric Chiral Ligands N2 - Spiropyridines, a novel series of C2-symmetric ligands, can be obtained in moderate yields by means of Co(I)-catalyzed double cocyclization between bis-alkynenitriles and alkynes. This one-step method allowed the first synthesis of the interesting 7,7‘- and 8,8‘-spyropyridines from acyclic precursors. ER -