%0 Journal Article %A Varela, Jesús A. %A Castedo, Luis %A Saá, Carlos %D 1999 %T One-Step Synthesis of Spiropyridines, a Novel Class of C2-Symmetric Chiral Ligands, by Cobalt(I)-Catalyzed [2 + 2 + 2] Cycloadditions between Bis-Alkynenitriles and Alkynes %U https://acs.figshare.com/articles/journal_contribution/One-Step_Synthesis_of_Spiropyridines_a_Novel_Class_of_i_C_i_sub_2_sub_-Symmetric_Chiral_Ligands_by_Cobalt_I_-Catalyzed_2_2_2_Cycloadditions_between_Bis-Alkynenitriles_and_Alkynes_sup_sup_/3761364 %R 10.1021/ol991195m.s001 %2 https://ndownloader.figshare.com/files/5868657 %K cocyclization %K C 2 %K alkyne %K synthesis %K method %K series %K Synthesi %K Spiropyridine %K Alkyne %K spyropyridine %K Co %K acyclic %K precursor %K ligand %K yield %K Cobalt %K Cycloaddition %K Symmetric Chiral Ligands %X Spiropyridines, a novel series of C2-symmetric ligands, can be obtained in moderate yields by means of Co(I)-catalyzed double cocyclization between bis-alkynenitriles and alkynes. This one-step method allowed the first synthesis of the interesting 7,7‘- and 8,8‘-spyropyridines from acyclic precursors. %I ACS Publications