A Novel Palladium-Catalyzed Intramolecular Redox Reaction Klemens Högenauer Johann Mulzer 10.1021/ol015813m.s001 https://acs.figshare.com/articles/journal_contribution/A_Novel_Palladium-Catalyzed_Intramolecular_Redox_Reaction/3739020 A new type of palladium-catalyzed redox reaction is described, forming enones from 2-(2-bromobenzyl)-ketones with an overall loss of HBr. The scope and limitations of the reaction are demonstrated by a series of cyclic and acyclic substrates. The mechanism most probably involves the formation of an intramolecular arylpalladium enolate and is related to the oxidation of silyl enol ethers with palladium acetate. 2001-04-05 00:00:00 intramolecular arylpalladium enolate series acyclic substrates Redox silyl enol ethers mechanism palladium acetate redox scope type HBr oxidation bromobenzyl formation enone limitation Intramolecular