10.1021/ol006145s.s001 Adam Golebiowski Adam Golebiowski Sean R. Klopfenstein Sean R. Klopfenstein Xia Shao Xia Shao Jack J. Chen Jack J. Chen Anny-Odile Colson Anny-Odile Colson Arthur L. Grieb Arthur L. Grieb Anne F. Russell Anne F. Russell Solid-Supported Synthesis of a Peptide β-Turn Mimetic American Chemical Society 2000 bicyclic diketopiperazine amine resin ester acid Peptide Ugi reaction synthesis peptide aldehyde bromo isocyanide Mimetic Synthesi 2000-08-03 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Solid-Supported_Synthesis_of_a_Peptide_-Turn_Mimetic/3736686 The solid-supported synthesis of a bicyclic diketopiperazine, a potential peptide β-turn mimetic, is described. The Ugi reaction between the resin ester of α-<i>N</i>-Boc-diaminopropionic acid (an amine input), α-bromo acid, aldehyde, and isocyanide is the key step in the proposed protocol.