10.1021/np990454d.s001 Yuan-Jian Xu Yuan-Jian Xu Xiao-Hua Wu Xiao-Hua Wu B. K. H. Tan B. K. H. Tan Yee-Hing Lai Yee-Hing Lai J. J. Vittal J. J. Vittal Z. Imiyabir Z. Imiyabir L. Madani L. Madani K. S. Khozirah K. S. Khozirah S. H. Goh S. H. Goh Flavonol−Cinnamate Cycloadducts and Diamide Derivatives from <i>Aglaia laxiflora</i> American Chemical Society 2000 adduct biosynthetic precursors trimethoxyflavonol crystallography Cycloadduct 2 D NMR spectroscopy stereochemistry Malaysian plant Aglaia laxiflora Flavonol cytotoxic compounds Diamide Derivatives flavonol aglaxiflorin rocaglaol rhamnoside Aglaia laxiflora Leaf extracts 2000-03-22 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Flavonol_Cinnamate_Cycloadducts_and_Diamide_Derivatives_from_i_Aglaia_laxiflora_i_/3734973 Leaf extracts of the Malaysian plant <i>Aglaia laxiflora </i>provided two cytotoxic compounds, a new rocaglaol rhamnoside (<b>1</b>), a known rocaglaol (<b>2</b>), new (but inactive) flavonol−cinnamaminopyrrolidine adducts (<b>3</b>−<b>6</b>), and their probable biosynthetic precursors (<b>7</b> and trimethoxyflavonol). All structures were elucidated primarily by 2D NMR spectroscopy. The structure and stereochemistry of aglaxiflorin A (<b>3</b>) were confirmed by single-crystal X-ray crystallography.