%0 Journal Article %A Chugunova, Elena A. %A Akylbekov, Nurgali I. %A Voloshina, Alexandra D. %A Kulik, Natalia V. %A Zobov, Vladimir V. %A Babaev, Vasily M. %A Gavrilov, Nikolai V. %A R. Burilov, Alexander %D 2016 %T Synthesis and investigation of antimicrobial activity of compounds derived from benzo[C][1,2,5]oxadiazole-1-oxides and phenolates %U https://tandf.figshare.com/articles/journal_contribution/Synthesis_and_Investigation_of_Antimicrobial_Activity_of_Compounds_Derived_from_Benzo_C_1_2_5_oxadiazole-1-oxides_and_Phenolates/3502034 %R 10.6084/m9.figshare.3502034.v2 %2 https://ndownloader.figshare.com/files/5534069 %K Antimicrobial activity %K benzofuroxan %K C-bonded product %K dual action %K phenolates %X

(Di)chloro(di)nitrobenzofuroxans form substitution products involving carbon atoms with phenolates in isopropyl alcohol medium. In the case of 4,6-dinitro-5,7-dichlorobenzofuroxan, besides replacement of one chlorine atom and the formation of C-bonded product, we observed the hydrolysis of the second chlorine and replacement of it by hydroxyl group. Products of reaction of 4,6-dichloro-5-nitrobenzofuroxan with phenolates display excellent antimicrobial activity and have dual action, both against bacteria and fungi.

%I Taylor & Francis