Gallium and Functionalized-Porphyrins Combine to Form
Potential Lysosome-Specific Multimodal Bioprobes
Jie Pan
Bethany I. Harriss
Chi-Fai Chan
Lijun Jiang
Tik-Hung Tsoi
Nicholas J. Long
Wing-Tak Wong
Wai-Kwok Wong
Ka-Leung Wong
10.1021/acs.inorgchem.6b01159.s001
https://acs.figshare.com/articles/journal_contribution/Gallium_and_Functionalized-Porphyrins_Combine_to_Form_Potential_Lysosome-Specific_Multimodal_Bioprobes/3467492
A water-soluble bimetallic
normal (“cold”) and radiochemical (“hot”)
gallium–porphyrin–ruthenium–bipyridine complex
(<b>GaporRu-1</b>) has been synthesized by microwave methodology
in short reaction times with
good (>85%) yields. <sup><b>68</b></sup><b>GaporRu-1</b> is demonstrated to be a potential multimodal and functional bioprobe
for positron emission tomography (PET), lysosome specific optical
imaging, and photodynamic therapy.
2016-06-29 17:21:22
lysosome
multimodal
radiochemical
photodynamic therapy
Bioprobe
reaction times
positron emission tomography
68 GaporRu
microwave methodology
bimetallic
Gallium
bioprobe
imaging
gallium
yield
Multimodal